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New photoreactive tRNA derivatives for probing the peptidyl transferase center of the ribosome

Three new photoreactive tRNA derivatives have been synthesized for use as probes of the peptidyl transferase center of the ribosome. In two of these derivatives, the 3′ adenosine of yeast tRNA(Phe) has been replaced by either 2-azidodeoxyadenosine or 2-azido-2′-O-methyl adenosine, while in a third t...

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Detalhes bibliográficos
Main Authors: Manuilov, Anton V., Hixson, Stephen S., Zimmermann, Robert A.
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1852821/
https://ncbi.nlm.nih.gov/pubmed/17379815
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.425907
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