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New photoreactive tRNA derivatives for probing the peptidyl transferase center of the ribosome

Three new photoreactive tRNA derivatives have been synthesized for use as probes of the peptidyl transferase center of the ribosome. In two of these derivatives, the 3′ adenosine of yeast tRNA(Phe) has been replaced by either 2-azidodeoxyadenosine or 2-azido-2′-O-methyl adenosine, while in a third t...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Manuilov, Anton V., Hixson, Stephen S., Zimmermann, Robert A.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Cold Spring Harbor Laboratory Press 2007
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1852821/
https://ncbi.nlm.nih.gov/pubmed/17379815
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.425907
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