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The interaction between C75 of tRNA and the A loop of the ribosome stimulates peptidyl transferase activity
Ribosomal variants carrying mutations in active site nucleotides are severely compromised in their ability to catalyze peptide bond formation (PT) with minimal aminoacyl tRNA substrates such as puromycin. However, catalysis of PT by these same ribosomes with intact aminoacyl tRNA substrates is uncom...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Copyright 2006 by RNA Society
2006
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1370883/ https://ncbi.nlm.nih.gov/pubmed/16373492 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.2256706 |
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