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The contributions of dsRNA structure to Dicer specificity and efficiency
Dicer processes long double-stranded RNA (dsRNA) and pre-microRNAs to generate the functional intermediates (short interfering RNAs and microRNAs) of the RNA interference pathway. Here we identify features of RNA structure that affect Dicer specificity and efficiency. The data presented show that va...
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| Main Authors: | , , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Copyright 2005 by RNA Society
2005
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1370754/ https://ncbi.nlm.nih.gov/pubmed/15811921 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.7272305 |
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