Intron function in the nonsense-mediated decay of beta-globin mRNA: indications that pre-mRNA splicing in the nucleus can influence mRNA translation in the cytoplasm.

Generally, mRNAs that prematurely terminate translation are abnormally low in abundance. In the case of mammalian cells, nonsense codons most often mediate a reduction in the abundance of newly synthesized, nucleus-associated mRNA by a mechanism that is not well understood. With the aim of defining...

Description complète

Enregistré dans:
Détails bibliographiques
Auteurs principaux: Zhang, J, Sun, X, Qian, Y, Maquat, L E
Format: Artigo
Langue:Inglês
Publié: 1998
Sujets:
Research Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC1369660/
https://ncbi.nlm.nih.gov/pubmed/9671053
Tags: Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!

Documents similaires