At Least One Intron Is Required for the Nonsense-Mediated Decay of Triosephosphate Isomerase mRNA: a Possible Link between Nuclear Splicing and Cytoplasmic Translation

Mammalian cells have established mechanisms to reduce the abundance of mRNAs that harbor a nonsense codon and prematurely terminate translation. In the case of the human triosephosphate isomerase (TPI gene), nonsense codons located less than 50 to 55 bp upstream of intron 6, the 3′-most intron, fail...

Полное описание

Библиографические подробности

Опубликовано в::	Mol Cell Biol
Главные авторы:	Zhang, Jing, Sun, Xiaolei, Qian, Yimei, LaDuca, Jeffrey P., Maquat, Lynne E.
Формат:	Artigo
Язык:	Inglês
Опубликовано:	Taylor & Francis 1998
Предметы:	Gene Expression
Online-ссылка:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC109113/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9710612/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.18.9.5272
Метки:	Добавить метку Нет меток, Требуется 1-ая метка записи!