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Cross-Packaging of a Single Adeno-Associated Virus (AAV) Type 2 Vector Genome into Multiple AAV Serotypes Enables Transduction with Broad Specificity
The serotypes of adeno-associated virus (AAV) have the potential to become important resources for clinical gene therapy. In an effort to compare the role of serotype-specific virion shells on vector transduction, we cloned each of the serotype capsid coding domains into a common vector backbone con...
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Główni autorzy: | , , , , , , |
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Format: | Artigo |
Język: | Inglês |
Wydane: |
American Society for Microbiology
2002
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Hasła przedmiotowe: | |
Dostęp online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC136844/ https://ncbi.nlm.nih.gov/pubmed/11752169 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.76.2.791-801.2002 |
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