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Adeno-Associated Virus (AAV) Versus Immune Response

Decades ago, Friedmann and Roblin postulated several barriers to gene therapy, including tissue targeting, delivery across the blood–brain barrier (BBB), and host immune responses. These issues remain pertinent till today. Since then, several advances have been made in elucidating structures of aden...

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Библиографические подробности
Опубликовано в: :Viruses
Главные авторы: Rabinowitz, Joseph, Chan, Ying Kai, Samulski, Richard Jude
Формат: Artigo
Язык:Inglês
Опубликовано: MDPI 2019
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC6409805/
https://ncbi.nlm.nih.gov/pubmed/30691064
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/v11020102
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