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Structure of Core Domain of Fibril-Forming PHF/Tau Fragments
Short peptide sequences within the microtubule binding domain of the protein Tau are proposed to be core nucleation sites for formation of amyloid fibrils displaying the paired helical filament (PHF) morphology characteristic of neurofibrillary tangles. To study the structure of these proposed nucle...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Biophysical Society
2006
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1367326/ https://ncbi.nlm.nih.gov/pubmed/16339876 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1529/biophysj.105.070136 |
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