載入...

Oxidative Stress Conditions Result in Trapping of PHF-Core Tau (297–391) Intermediates

The self-assembly of tau into paired helical filaments (PHFs) in neurofibrillary tangles (NFTs) is a significant event in Alzheimer’s disease (AD) pathogenesis. Numerous post-translational modifications enhance or inhibit tau assembly into NFTs. Oxidative stress, which accompanies AD, induces multip...

全面介紹

Na minha lista:
書目詳細資料
發表在:Cells
Main Authors: Maina, Mahmoud B., Al-Hilaly, Youssra K., Burra, Gunasekhar, Rickard, Janet E., Harrington, Charles R., Wischik, Claude M., Serpell, Louise C.
格式: Artigo
語言:Inglês
出版: MDPI 2021
主題:
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC8005035/
https://ncbi.nlm.nih.gov/pubmed/33809978
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cells10030703
標簽: 添加標簽
沒有標簽, 成為第一個標記此記錄!