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Tau (297‐391) forms filaments that structurally mimic the core of paired helical filaments in Alzheimer’s disease brain
The constituent paired helical filaments (PHFs) in neurofibrillary tangles are insoluble intracellular deposits central to the development of Alzheimer’s disease (AD) and other tauopathies. Full‐length tau requires the addition of anionic cofactors such as heparin to enhance assembly. We have shown...
Αποθηκεύτηκε σε:
| Τόπος έκδοσης: | FEBS Lett |
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| Κύριοι συγγραφείς: | , , , , , , , , , , |
| Μορφή: | Artigo |
| Γλώσσα: | Inglês |
| Έκδοση: |
John Wiley and Sons Inc.
2019
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| Θέματα: | |
| Διαθέσιμο Online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7078754/ https://ncbi.nlm.nih.gov/pubmed/31721178 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/1873-3468.13675 |
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