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Fibril-Forming Motifs Are Essential and Sufficient for the Fibrillization of Human Tau

BACKGROUND: The misfolding of amyloidogenic proteins including human Tau protein, human prion protein, and human α-synuclein is involved in neurodegenerative diseases such as Alzheimer disease, prion disease, and Parkinson disease. Although a lot of research on such amyloidogenic proteins has been d...

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Detalhes bibliográficos
Main Authors: Meng, Sheng-Rong, Zhu, Ying-Zhu, Guo, Tong, Liu, Xiao-Ling, Chen, Jie, Liang, Yi
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3372541/
https://ncbi.nlm.nih.gov/pubmed/22701727
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0038903
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