טוען...
Fibrillization of Human Tau Is Accelerated by Exposure to Lead via Interaction with His-330 and His-362
BACKGROUND: Neurofibrillary tangles, mainly consisted of bundles of filaments formed by the microtubule-associated protein Tau, are a hallmark of Alzheimer disease. Lead is a potent neurotoxin for human being especially for the developing children, and Pb(2+) at high concentrations is found in the b...
שמור ב:
| Main Authors: | , , , , |
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| פורמט: | Artigo |
| שפה: | Inglês |
| יצא לאור: |
Public Library of Science
2011
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| נושאים: | |
| גישה מקוונת: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3180286/ https://ncbi.nlm.nih.gov/pubmed/21966400 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0025020 |
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