Llwytho...

A Ca(2+)-Binding Domain in RyR1 that Interacts with the Calmodulin Binding Site and Modulates Channel Activity

A fragment of RyR1 (amino acids 4064–4210) is predicted to fold to at least one lobe of calmodulin and to bind Ca(2+). This fragment of RyR1 (R4064–4210) was subcloned, expressed, refolded, and purified. Consistent with the predicted folding pattern, R4064–4210 was found to bind two molecules of Ca(...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Xiong, Liangwen, Zhang, Jia-Zheng, He, Rong, Hamilton, Susan L.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Biophysical Society 2006
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC1367016/
https://ncbi.nlm.nih.gov/pubmed/16227507
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1529/biophysj.105.066092
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