Cargando...
Ca(2+)-dependent calmodulin binding to cardiac ryanodine receptor (RyR2) calmodulin-binding domains
The Ca(2+) sensor calmodulin (CaM) regulates cardiac ryanodine receptor (RyR2)-mediated Ca(2+) release from the sarcoplasmic reticulum. CaM inhibits RyR2 in a Ca(2+)-dependent manner and aberrant CaM-dependent inhibition results in life-threatening cardiac arrhythmias. However, the molecular details...
Gardado en:
| Publicado en: | Biochem J |
|---|---|
| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
Portland Press Ltd.
2019
|
| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6340113/ https://ncbi.nlm.nih.gov/pubmed/30530841 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BCJ20180545 |
| Tags: |
Engadir etiqueta
Sen Etiquetas, Sexa o primeiro en etiquetar este rexistro!
|