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Predicting the Tolerance of Proteins to Random Amino Acid Substitution
We have recently proposed a thermodynamic model that predicts the tolerance of proteins to random amino acid substitutions. Here we test this model against extensive simulations with compact lattice proteins, and find that the overall performance of the model is very good. We also derive an approxim...
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| 主要な著者: | , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Biophysical Society
2005
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1366941/ https://ncbi.nlm.nih.gov/pubmed/16150971 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1529/biophysj.105.062125 |
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