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Predicting the Tolerance of Proteins to Random Amino Acid Substitution
We have recently proposed a thermodynamic model that predicts the tolerance of proteins to random amino acid substitutions. Here we test this model against extensive simulations with compact lattice proteins, and find that the overall performance of the model is very good. We also derive an approxim...
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| Auteurs principaux: | , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Biophysical Society
2005
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1366941/ https://ncbi.nlm.nih.gov/pubmed/16150971 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1529/biophysj.105.062125 |
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