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Thermodynamics of Neutral Protein Evolution
Naturally evolving proteins gradually accumulate mutations while continuing to fold to stable structures. This process of neutral evolution is an important mode of genetic change and forms the basis for the molecular clock. We present a mathematical theory that predicts the number of accumulated mut...
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| Главные авторы: | , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Copyright © 2007 by the Genetics Society of America
2007
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1775007/ https://ncbi.nlm.nih.gov/pubmed/17110496 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.106.061754 |
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