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Thermodynamics of Neutral Protein Evolution

Naturally evolving proteins gradually accumulate mutations while continuing to fold to stable structures. This process of neutral evolution is an important mode of genetic change and forms the basis for the molecular clock. We present a mathematical theory that predicts the number of accumulated mut...

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Detaylı Bibliyografya
Asıl Yazarlar: Bloom, Jesse D., Raval, Alpan, Wilke, Claus O.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Copyright © 2007 by the Genetics Society of America 2007
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC1775007/
https://ncbi.nlm.nih.gov/pubmed/17110496
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.106.061754
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