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Predicting Deleterious Amino Acid Substitutions
Many missense substitutions are identified in single nucleotide polymorphism (SNP) data and large-scale random mutagenesis projects. Each amino acid substitution potentially affects protein function. We have constructed a tool that uses sequence homology to predict whether a substitution affects pro...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
Cold Spring Harbor Laboratory Press
2001
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| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC311071/ https://ncbi.nlm.nih.gov/pubmed/11337480 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.176601 |
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