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In Silico profiling of deleterious amino acid substitutions of potential pathological importance in haemophlia A and haemophlia B

BACKGROUND: In this study, instead of current biochemical methods, the effects of deleterious amino acid substitutions in F8 and F9 gene upon protein structure and function were assayed by means of computational methods and information from the databases. Deleterious substitutions of F8 and F9 are r...

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Detalhes bibliográficos
Autor principal: C, George Priya Doss
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3361463/
https://ncbi.nlm.nih.gov/pubmed/22423892
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1423-0127-19-30
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