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De novo, systemic, deleterious amino acid substitutions are common in large cytoskeleton-related protein coding regions
Human mutagenesis is largely random, thus large coding regions, simply on the basis of probability, represent relatively large mutagenesis targets. Thus, we considered the possibility that large cytoskeletal-protein related coding regions (CPCRs), including extra-cellular matrix (ECM) coding regions...
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Publicado no: | Biomed Rep |
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Main Authors: | , , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
D.A. Spandidos
2017
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5351269/ https://ncbi.nlm.nih.gov/pubmed/28357075 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/br.2016.826 |
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