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De novo, systemic, deleterious amino acid substitutions are common in large cytoskeleton-related protein coding regions

Human mutagenesis is largely random, thus large coding regions, simply on the basis of probability, represent relatively large mutagenesis targets. Thus, we considered the possibility that large cytoskeletal-protein related coding regions (CPCRs), including extra-cellular matrix (ECM) coding regions...

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Detalhes bibliográficos
Publicado no:Biomed Rep
Main Authors: Stoll, Rebecca J., Thompson, Grace R., Samy, Mohammad D., Blanck, George
Formato: Artigo
Idioma:Inglês
Publicado em: D.A. Spandidos 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5351269/
https://ncbi.nlm.nih.gov/pubmed/28357075
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/br.2016.826
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