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De novo, systemic, deleterious amino acid substitutions are common in large cytoskeleton-related protein coding regions

Human mutagenesis is largely random, thus large coding regions, simply on the basis of probability, represent relatively large mutagenesis targets. Thus, we considered the possibility that large cytoskeletal-protein related coding regions (CPCRs), including extra-cellular matrix (ECM) coding regions...

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Publicat a:Biomed Rep
Autors principals: Stoll, Rebecca J., Thompson, Grace R., Samy, Mohammad D., Blanck, George
Format: Artigo
Idioma:Inglês
Publicat: D.A. Spandidos 2017
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5351269/
https://ncbi.nlm.nih.gov/pubmed/28357075
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/br.2016.826
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