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Coarse-Grained Strategy for Modeling Protein Stability in Concentrated Solutions
We present a coarse-grained approach for modeling the thermodynamic stability of single-domain globular proteins in concentrated aqueous solutions. Our treatment derives effective protein-protein interactions from basic structural and energetic characteristics of the native and denatured states. The...
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| Autori principali: | , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Biophysical Society
2005
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| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1366737/ https://ncbi.nlm.nih.gov/pubmed/16040749 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1529/biophysj.105.062067 |
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