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A Coarse-Grained Model for Force-Induced Protein Deformation and Kinetics

Force-induced changes in protein conformation are thought to be responsible for certain cellular responses to mechanical force. Changes in conformation subsequently initiate a biochemical response by alterations in, for example, binding affinity to another protein or enzymatic activity. Here, a mode...

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Detalhes bibliográficos
Main Authors: Karcher, Helene, Lee, Seung E., Kaazempur-Mofrad, Mohammad R., Kamm, Roger D.
Formato: Artigo
Idioma:Inglês
Publicado em: Biophysical Society 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1414568/
https://ncbi.nlm.nih.gov/pubmed/16443661
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1529/biophysj.104.054841
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