Folding Trp-Cage to NMR Resolution Native Structure Using a Coarse-Grained Protein Model

We develop a coarse-grained protein model with a simplified amino acid interaction potential. Using this model, we perform discrete molecular dynamics folding simulations of a small 20-residue protein—Trp-cage—from a fully extended conformation. We demonstrate the ability of the Trp-cage model to co...

Ful tanımlama

Kaydedildi:
Detaylı Bibliyografya
Asıl Yazarlar: Ding, Feng, Buldyrev, Sergey V., Dokholyan, Nikolay V.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: The Biophysical Society 2005
Konular:
Biophysical Theory and Modeling
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC1304993/
https://ncbi.nlm.nih.gov/pubmed/15533926
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1529/biophysj.104.046375
Etiketler: Etiketle
Etiket eklenmemiş, İlk siz ekleyin!

Benzer Materyaller