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Multiple Folding Pathways of the SH3 Domain

Experimental observations suggest that proteins follow different folding pathways under different environmental conditions. We perform molecular dynamics simulations of a model of the c-Crk SH3 domain over a broad range of temperatures, and identify distinct pathways in the folding transition. We de...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Borreguero, Jose M., Ding, Feng, Buldyrev, Sergey V., Stanley, H. Eugene, Dokholyan, Nikolay V.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Biophysical Society 2004
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1304373/
https://ncbi.nlm.nih.gov/pubmed/15240485
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1529/biophysj.104.039529
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