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Direct molecular dynamics observation of protein folding transition state ensemble.

The concept of the protein transition state ensemble (TSE), a collection of the conformations that have 50% probability to convert rapidly to the folded state and 50% chance to rapidly unfold, constitutes the basis of the modern interpretation of protein engineering experiments. It has been conjectu...

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Detalhes bibliográficos
Main Authors: Ding, Feng, Dokholyan, Nikolay V, Buldyrev, Sergey V, Stanley, H Eugene, Shakhnovich, Eugene I
Formato: Artigo
Idioma:Inglês
Publicado em: 2002
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1302427/
https://ncbi.nlm.nih.gov/pubmed/12496119
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