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Formation of the Folding Nucleus of an SH3 Domain Investigated by Loosely Coupled Molecular Dynamics Simulations

The experimentally well-established folding mechanism of the src-SH3 domain, and in particular the φ-value analysis of its transition state, represents a sort of testing table for computational investigations of protein folding. Here, parallel molecular dynamics simulations of the src-SH3 domain hav...

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Detalhes bibliográficos
Main Authors: Settanni, G., Gsponer, J., Caflisch, A.
Formato: Artigo
Idioma:Inglês
Publicado em: Biophysical Society 2004
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1304005/
https://ncbi.nlm.nih.gov/pubmed/14990497
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