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Coarse-Grained Strategy for Modeling Protein Stability in Concentrated Solutions. II: Phase Behavior
We use highly efficient transition-matrix Monte Carlo simulations to determine equilibrium unfolding curves and fluid phase boundaries for solutions of coarse-grained globular proteins. The model we analyze derives the intrinsic stability of the native state and protein-protein interactions from bas...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Biophysical Society
2006
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1386775/ https://ncbi.nlm.nih.gov/pubmed/16387768 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1529/biophysj.105.076497 |
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