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Probing the Role of Negatively Charged Amino Acid Residues in Ion Permeation of Skeletal Muscle Ryanodine Receptor

Sequence comparison suggests that the ryanodine receptors (RyRs) have pore architecture similar to that of the bacterial K(+) channel KcsA. The lumenal loop linking the two most C-terminal transmembrane spanning segments in the RyRs has a predicted pore helix and an amino acid motif (GGGIG) similar...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Wang, Ying, Xu, Le, Pasek, Daniel A., Gillespie, Dirk, Meissner, Gerhard
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Biophysical Society 2005
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC1366523/
https://ncbi.nlm.nih.gov/pubmed/15863483
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1529/biophysj.104.056002
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