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Two Rings of Negative Charges in the Cytosolic Vestibule of Type-1 Ryanodine Receptor Modulate Ion Fluxes
The tetrameric ryanodine receptor calcium release channels (RyRs) are cation-selective channels that have pore architecture similar to that of K(+) channels. We recently identified, in close proximity to the selectivity filter motif GGGIG, a conserved lumenal DE motif that has a critical role in RyR...
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| Autores principales: | , , , |
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
Biophysical Society
2006
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1367051/ https://ncbi.nlm.nih.gov/pubmed/16239337 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1529/biophysj.105.072538 |
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