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Probing the Local Dynamics of Nucleotide-Binding Pocket Coupled to the Global Dynamics: Myosin versus Kinesin

Based on the elastic network model, we develop a new analysis for protein complexes, which probes the local dynamics of a subsystem that is elastically coupled to a fluctuating environment. This method is applied to a comparative dynamical analysis of the nucleotide-binding pocket of two motor prote...

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Detalhes bibliográficos
Main Authors: Zheng, Wenjun, Brooks, Bernard R.
Formato: Artigo
Idioma:Inglês
Publicado em: Biophysical Society 2005
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1366515/
https://ncbi.nlm.nih.gov/pubmed/15879477
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1529/biophysj.105.063305
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