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Coupling of Global and Local Vibrational Modes in Dynamic Allostery of Proteins
It is now recognized that internal global protein dynamics play an important role in the allosteric function of many proteins. Alterations of protein flexibility on effector binding affect the entropic cost of binding at a distant site. We present a coarse-grained model for a potential amplification...
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| 主要な著者: | , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Biophysical Society
2006
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1557547/ https://ncbi.nlm.nih.gov/pubmed/16798805 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1529/biophysj.106.082180 |
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