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Coupling of Global and Local Vibrational Modes in Dynamic Allostery of Proteins

It is now recognized that internal global protein dynamics play an important role in the allosteric function of many proteins. Alterations of protein flexibility on effector binding affect the entropic cost of binding at a distant site. We present a coarse-grained model for a potential amplification...

詳細記述

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書誌詳細
主要な著者: Hawkins, Rhoda J., McLeish, Tom C. B.
フォーマット: Artigo
言語:Inglês
出版事項: Biophysical Society 2006
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC1557547/
https://ncbi.nlm.nih.gov/pubmed/16798805
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1529/biophysj.106.082180
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