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Computational analysis of dynamic allostery and control in the SARS-CoV-2 main protease

The COVID-19 pandemic caused by the novel coronavirus SARS-CoV-2 has no publicly available vaccine or antiviral drugs at the time of writing. An attractive coronavirus drug target is the main protease (M(pro), also known as 3CL(pro)) because of its vital role in the viral cycle. A significant body o...

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Bibliografiska uppgifter
I publikationen:J R Soc Interface
Huvudupphovsmän: Dubanevics, Igors, McLeish, Tom C. B.
Materialtyp: Artigo
Språk:Inglês
Publicerad: The Royal Society 2021
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC7879766/
https://ncbi.nlm.nih.gov/pubmed/33402024
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1098/rsif.2020.0591
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