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Computational analysis of dynamic allostery and control in the SARS-CoV-2 main protease

The COVID-19 pandemic caused by the novel coronavirus SARS-CoV-2 has no publicly available vaccine or antiviral drugs at the time of writing. An attractive coronavirus drug target is the main protease (M(pro), also known as 3CL(pro)) because of its vital role in the viral cycle. A significant body o...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:J R Soc Interface
Prif Awduron: Dubanevics, Igors, McLeish, Tom C. B.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: The Royal Society 2021
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC7879766/
https://ncbi.nlm.nih.gov/pubmed/33402024
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1098/rsif.2020.0591
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