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The Kinesin-1 Tail Conformationally Restricts the Nucleotide Pocket

We have used electron paramagnetic resonance and fluorescence spectroscopy to study the interaction between the kinesin-1 head and its regulatory tail domain. The interaction between the tails and the enzymatically active heads has been shown to inhibit intrinsic and microtubule-stimulated ADP relea...

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Hlavní autoři: Wong, Yao Liang, Dietrich, Kristen A., Naber, Nariman, Cooke, Roger, Rice, Sarah E.
Médium: Artigo
Jazyk:Inglês
Vydáno: The Biophysical Society 2009
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2711265/
https://ncbi.nlm.nih.gov/pubmed/19348763
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2008.11.069
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