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Coupling between Normal Modes Drives Protein Conformational Dynamics: Illustrations Using Allosteric Transitions in Myosin II

Structure-based elastic network models (ENMs) have been remarkably successful in describing conformational transitions in a variety of biological systems. Low-frequency normal modes are usually calculated from the ENM that characterizes elastic interactions between residues in contact in a given pro...

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Detalhes bibliográficos
Main Authors: Zheng, Wenjun, Thirumalai, D.
Formato: Artigo
Idioma:Inglês
Publicado em: The Biophysical Society 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2717279/
https://ncbi.nlm.nih.gov/pubmed/19289039
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2008.12.3897
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