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Allosteric Transitions in Biological Nanomachines are Described by Robust Normal Modes of Elastic Networks

Allostery forms the basis of intra-molecular communications in various enzymes, however the underlying conformational changes are largely elusive. Recently, we have proposed to employ an elastic model based normal mode analysis to investigate the allosteric transitions in several molecular nanomachi...

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Detalhes bibliográficos
Main Authors: Zheng, Wenjun, Brooks, Bernard R., Thirumalai, D
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3610319/
https://ncbi.nlm.nih.gov/pubmed/19355980
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