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Anharmonic Normal Mode Analysis of Elastic Network Model Improves the Modeling of Atomic Fluctuations in Protein Crystal Structures

Protein conformational dynamics, despite its significant anharmonicity, has been widely explored by normal mode analysis (NMA) based on atomic or coarse-grained potential functions. To account for the anharmonic aspects of protein dynamics, this study proposes, and has performed, an anharmonic NMA (...

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Autor principal: Zheng, Wenjun
Format: Artigo
Idioma:Inglês
Publicat: The Biophysical Society 2010
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2884254/
https://ncbi.nlm.nih.gov/pubmed/20550915
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2010.03.027
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