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Anharmonic Normal Mode Analysis of Elastic Network Model Improves the Modeling of Atomic Fluctuations in Protein Crystal Structures

Protein conformational dynamics, despite its significant anharmonicity, has been widely explored by normal mode analysis (NMA) based on atomic or coarse-grained potential functions. To account for the anharmonic aspects of protein dynamics, this study proposes, and has performed, an anharmonic NMA (...

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Detalles Bibliográficos
Autor Principal: Zheng, Wenjun
Formato: Artigo
Idioma:Inglês
Publicado: The Biophysical Society 2010
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2884254/
https://ncbi.nlm.nih.gov/pubmed/20550915
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2010.03.027
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