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Inherent properties of somatic hypermutation as revealed by human non-productive VH6 immunoglobulin rearrangements.

To study inherent properties of somatic hypermutation of human immunoglobulin genes in the absence of antigen selection, mutations of human non-productive VH6 rearrangements enriched by subtractive hybridization were characterized. Ten unique clones arising from nine non-productive rearrangements we...

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Detalhes bibliográficos
Main Authors: Varade, W S, Carnahan, J A, Kingsley, P D, Insel, R A
Formato: Artigo
Idioma:Inglês
Publicado em: 1998
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1364175/
https://ncbi.nlm.nih.gov/pubmed/9616365
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