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Inherent properties of somatic hypermutation as revealed by human non-productive VH6 immunoglobulin rearrangements.

To study inherent properties of somatic hypermutation of human immunoglobulin genes in the absence of antigen selection, mutations of human non-productive VH6 rearrangements enriched by subtractive hybridization were characterized. Ten unique clones arising from nine non-productive rearrangements we...

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Autori principali: Varade, W S, Carnahan, J A, Kingsley, P D, Insel, R A
Natura: Artigo
Lingua:Inglês
Pubblicazione: 1998
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1364175/
https://ncbi.nlm.nih.gov/pubmed/9616365
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