Altered Substrate Specificity of Drug-Resistant Human Immunodeficiency Virus Type 1 Protease

Resistance to human immunodeficiency virus type 1 protease (HIV PR) inhibitors results primarily from the selection of multiple mutations in the protease region. Because many of these mutations are selected for the ability to decrease inhibitor binding in the active site, they also affect substrate...

Celý popis

Uloženo v:
Podrobná bibliografie
Hlavní autoři: Dauber, Deborah S., Ziermann, Rainer, Parkin, Neil, Maly, Dustin J., Mahrus, Sami, Harris, Jennifer L., Ellman, Jon A., Petropoulos, Christos, Craik, Charles S.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2002
Témata:
Vaccines and Antiviral Agents
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC135855/
https://ncbi.nlm.nih.gov/pubmed/11773410
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.76.3.1359-1368.2002
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky