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Temperature-dependent splicing of β-globin pre-mRNA

A T→G mutation at nucleotide 705 of human β-globin intron 2 creates an aberrant 5′ splice site and activates a cryptic 3′ splice site upstream. In consequence, the pre-mRNA is spliced via aberrant splice sites, despite the presence of the still functional correct sites. Surprisingly, when IVS2-705 H...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Gemignani, Federica, Sazani, Peter, Morcos, Paul, Kole, Ryszard
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Oxford University Press 2002
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC135830/
https://ncbi.nlm.nih.gov/pubmed/12409448
Etiketak: Etiketa erantsi
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