Temperature-dependent splicing of β-globin pre-mRNA

A T→G mutation at nucleotide 705 of human β-globin intron 2 creates an aberrant 5′ splice site and activates a cryptic 3′ splice site upstream. In consequence, the pre-mRNA is spliced via aberrant splice sites, despite the presence of the still functional correct sites. Surprisingly, when IVS2-705 H...

Descripció completa

Dades bibliogràfiques

Publicat a:	Nucleic Acids Res
Autors principals:	Gemignani, Federica, Sazani, Peter, Morcos, Paul, Kole, Ryszard
Format:	Artigo
Idioma:	Inglês
Publicat:	Oxford University Press 2002
Matèries:	Articles
Accés en línia:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC135830/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12409448/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/gkf607
Etiquetes:	Afegir etiqueta Sense etiquetes, Sigues el primer a etiquetar aquest registre!