Antibodies to hnRNP core proteins inhibit in vitro splicing of human beta-globin pre-mRNA.
In vitro splicing of human beta-globin pre-mRNA can be fully inhibited by treatment of the splicing extract with polyclonal antibodies against hnRNP core proteins prior to the addition of pre-mRNA. Inhibition of the first step in the splicing pathway, cleavage at the 5' splice site and lariat format...
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| Опубликовано в:: | Nucleic Acids Res |
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| Главные авторы: | , , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Oxford University Press
1986
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| Online-ссылка: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC311538/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3737400/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/14.13.5241 |
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