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Antibodies to hnRNP core proteins inhibit in vitro splicing of human beta-globin pre-mRNA.

In vitro splicing of human beta-globin pre-mRNA can be fully inhibited by treatment of the splicing extract with polyclonal antibodies against hnRNP core proteins prior to the addition of pre-mRNA. Inhibition of the first step in the splicing pathway, cleavage at the 5' splice site and lariat format...

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Bibliografiska uppgifter
I publikationen:Nucleic Acids Res
Huvudupphov: Sierakowska, H, Szer, W, Furdon, P J, Kole, R
Materialtyp: Artigo
Språk:Inglês
Utgiven: Oxford University Press 1986
Länkar:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC311538/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3737400/
https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/14.13.5241
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