Immunization with Chaperone-Peptide Complex Induces Low-Avidity Cytotoxic T Lymphocytes Providing Transient Protection against Herpes Simplex Virus Infection

Heat shock proteins loaded with viral peptides were shown to induce a CD8(+) T cell response and confer protective immunity against challenge with herpes simplex virus (HSV). The delivery system consisted of recombinant human hsp70 coupled to the peptide SSIEFARL, which is the immunodominant peptide...

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發表在:	J Virol
Principais autores:	Kumaraguru, Udayasankar, Gierynska, Malgorzata, Norman, Shanna, Bruce, Barry D., Rouse, Barry T.
格式:	Artigo
語言:	Inglês
出版:	American Society for Microbiology (ASM) 2002
主題:	Vaccines and Antiviral Agents
在線閱讀:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC135705/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11739679/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/JVI.76.1.136-141.2002
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