Immunization with Chaperone-Peptide Complex Induces Low-Avidity Cytotoxic T Lymphocytes Providing Transient Protection against Herpes Simplex Virus Infection

Heat shock proteins loaded with viral peptides were shown to induce a CD8(+) T cell response and confer protective immunity against challenge with herpes simplex virus (HSV). The delivery system consisted of recombinant human hsp70 coupled to the peptide SSIEFARL, which is the immunodominant peptide...

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Cyhoeddwyd yn:	J Virol
Prif Awduron:	Kumaraguru, Udayasankar, Gierynska, Malgorzata, Norman, Shanna, Bruce, Barry D., Rouse, Barry T.
Fformat:	Artigo
Iaith:	Inglês
Cyhoeddwyd:	American Society for Microbiology (ASM) 2002
Pynciau:	Vaccines and Antiviral Agents
Mynediad Ar-lein:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC135705/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11739679/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/JVI.76.1.136-141.2002
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