Immunization with Chaperone-Peptide Complex Induces Low-Avidity Cytotoxic T Lymphocytes Providing Transient Protection against Herpes Simplex Virus Infection

Heat shock proteins loaded with viral peptides were shown to induce a CD8(+) T cell response and confer protective immunity against challenge with herpes simplex virus (HSV). The delivery system consisted of recombinant human hsp70 coupled to the peptide SSIEFARL, which is the immunodominant peptide...

ver descrição completa

Detalhes bibliográficos

Publicado no:	J Virol
Principais autores:	Kumaraguru, Udayasankar, Gierynska, Malgorzata, Norman, Shanna, Bruce, Barry D., Rouse, Barry T.
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 2002
Assuntos:	Vaccines and Antiviral Agents
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC135705/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11739679/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/JVI.76.1.136-141.2002
Tags:	Adicionar Tag Sem tags, seja o primeiro a adicionar uma tag!