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Induction of CD8 T-Cell-Specific Systemic and Mucosal Immunity against Herpes Simplex Virus with CpG-Peptide Complexes
Oligodeoxynucleotides (ODN) containing unmethylated CpG motifs exert powerful adjuvant activity in vivo and in vitro. Administered with antigen they induce a population of antigen-specific CD8(+) T cells. In this study we immunized C57BL/6 mice with bioactive CpG ODN combined with an immunodominant...
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| Autores principales: | , , , , , |
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
American Society for Microbiology
2002
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC136257/ https://ncbi.nlm.nih.gov/pubmed/12050369 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.76.13.6568-6576.2002 |
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